AN INNOVATIVE
PHARMACEUTICAL COMPANY WITH
GROUNDBREAKING PATENTS
Groundbreaking Products
Auxesis is developing multiple formulations that block pain signals to the brain, effectively eliminating pain on the skin.
Our research focuses on products for human use, with potential applications for pets and livestock, though specific formulation adjustments may be required for different animal species. Additionally, the cosmetics and skincare industry represents another key target market.
Auxesis Stabilizes ASA in Liquid Form
Acetylsalicylic acid (ASA) is one of the most well-known pain-relieving substances and has been used in medications since the late 1800s, including Treo, Bamyl, and Aspirin.
After years of research and thousands of trials, Auxesis, in collaboration with Professor Moustapha Hassan and his team, has achieved what no one else has done before: stabilizing ASA in liquid form.
With liquid ASA, entirely new formulations can be developed, allowing for easy direct application to the skin, effectively relieving pain or irritation within minutes. By adding other pharmaceutically active substances, the effect is sustained until the body has healed itself. Studies indicate that the substance remains on the skin and does not enter the bloodstream.
The History of Acetylsalicylic Acid (ASA)
In herbal medicine, salicylic acid—a natural compound related to synthetic aspirin—has been used since ancient times, dating back at least to 2500 BCE. It is extracted from plants such as myrtle, willow, and meadowsweet.
In 1897, Dr. Felix Hoffmann, a German scientist at Friedrich Bayer & Co., successfully synthesized acetylsalicylic acid (ASA) for oral use for the first time.
This breakthrough marked the birth of both Aspirin and the modern pharmaceutical industry.
How Aspirin and Other Anti-Inflammatory Drugs Work
In the 1970s, researchers discovered that damage to human tissue triggers the release of prostaglandins—hormone-like molecules that cause fever and inflammation.
They also found that aspirin blocks the production of these molecules, though the exact mechanism was initially unclear.
Other anti-inflammatory drugs, such as Ibuprofen and Naproxen, work by physically blocking enzyme channels rather than chemically altering them.
What Is Skin Pain and How Does the Body React?
The nerve pathways that connect the peripheral nervous system to the brain transport information from various sensory receptors, which the brain processes into sensations.
These pathways, known as sensory nerves, transmit signals related to touch, heat, cold, and pain.
A fundamental characteristic of the first-order neurons in the tactile system—which extend into the skin to detect touch—is that each neuron’s fiber branches out, forming multiple sensitive zones across the skin.
The skin, along with nearly the entire body, contains pain receptors that respond to heat, cold, inflammation, and injury. These receptors send signals through nerve cells to the brain, where the information is transmitted as electrical impulses.
